Evaluation of E. faecalis Proteome from Endodontic Infection by Mass Spectrometry: A Preliminary Study

 

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Autoři: Retana-Lobo, Cristina, Davila Pérez, Claudia Edith, Ramírez-Mora, Tatiana
Médium: artículo original
Stav:Versión publicada
Datum vydání:2026
Popis:Proteins are a key to a deeper understanding of the behavior of Gram positive bacteria such as Enterococcus faecalis, one of the most frequently detected species in root canal-treated teeth, with a high prevalence report.  Such proteins contribute to cell wall synthesis and maintenance and are important for interactions between the bacterial cell and the human host. An E. faecalis strain isolated from root canal treatment failure and an ATCC strain was used for the proeomic analysis using Mass spectrometry. A total of 22 proteins were identified the majority of protein found were related to metabolic and housekeeping process, including metabolism energy, and protein synthesis. The present proteome analysis gives an experimental impression of the protein landscape of the pathogenic bacterium E. faecalis. These proteins stand out as interesting targets for further investigation of the interaction between E. faecalis and its root canal environment.
Země:Portal de Revistas UCR
Instituce:Universidad de Costa Rica
Repositorio:Portal de Revistas UCR
Jazyk:Inglés
OAI Identifier:oai:portal.revistas.ucr.ac.cr:article/12687
On-line přístup:https://revistas.ucr.ac.cr/index.php/rOdontos/article/view/12687
Klíčové slovo:Root canal treatment; Enterococcus faecalis; Treatment failure; Proteomic; Mass spectrometry; Cellular metabolism.
Tratamiento de conductos radiculares; Enterococcus faecalis; Fracaso de tratamiento; Proteomica; Espectrometría de masas; Metabolismo celular.