Evaluation of E. faecalis Proteome from Endodontic Infection by Mass Spectrometry: A Preliminary Study

 

Salvato in:
Dettagli Bibliografici
Autori: Retana-Lobo, Cristina, Davila Pérez, Claudia Edith, Ramírez-Mora, Tatiana
Natura: artículo original
Status:Versión publicada
Data di pubblicazione:2026
Descrizione:Proteins are a key to a deeper understanding of the behavior of Gram positive bacteria such as Enterococcus faecalis, one of the most frequently detected species in root canal-treated teeth, with a high prevalence report.  Such proteins contribute to cell wall synthesis and maintenance and are important for interactions between the bacterial cell and the human host. An E. faecalis strain isolated from root canal treatment failure and an ATCC strain was used for the proeomic analysis using Mass spectrometry. A total of 22 proteins were identified the majority of protein found were related to metabolic and housekeeping process, including metabolism energy, and protein synthesis. The present proteome analysis gives an experimental impression of the protein landscape of the pathogenic bacterium E. faecalis. These proteins stand out as interesting targets for further investigation of the interaction between E. faecalis and its root canal environment.
Stato:Portal de Revistas UCR
Istituzione:Universidad de Costa Rica
Repositorio:Portal de Revistas UCR
Lingua:Inglés
OAI Identifier:oai:portal.revistas.ucr.ac.cr:article/12687
Accesso online:https://revistas.ucr.ac.cr/index.php/rOdontos/article/view/12687
Keyword:Root canal treatment; Enterococcus faecalis; Treatment failure; Proteomic; Mass spectrometry; Cellular metabolism.
Tratamiento de conductos radiculares; Enterococcus faecalis; Fracaso de tratamiento; Proteomica; Espectrometría de masas; Metabolismo celular.