Progreso médico: encefalitis autoinmune contra el receptor de N-metil-D-aspartato asociada a teratomas

 

שמור ב:
מידע ביבליוגרפי
Autores: Cordero Morelo, Isabela, Camacho Solís, Ana Elena, Sainz Mejías, Amaya, Araya Molina, Carlos
פורמט: artículo original
סטטוס:Versión publicada
Fecha de Publicación:2019
תיאור:Autoimmune encephalitis against the N-methyl-D-aspartate receptor (NMDA-R) is a newly discovered disease that occurs mainly in young women. It is characterized by the presence of autoantibodies against NMDA receptor, specifically against the GluN1 subunit; which generates psychotic symptoms, movement disorders, autonomic dysfunction and even coma. About 50% of patients present ovarian teratoma when completing the studies. This disease is reversible and treatable, therefore diagnosis and treatment are essential. The first line of treatment includes steroids, intravenous G immunoglobulin or plasmapheresis. The second line consists of rituximab and cyclophosphamide. In addition, in the cases where a tumor is documented, the extirpation of it is considered fundamental.
País:Portal de Revistas UCR
מוסד:Universidad de Costa Rica
Repositorio:Portal de Revistas UCR
שפה:Español
OAI Identifier:oai:portal.ucr.ac.cr:article/37405
גישה מקוונת:https://revistas.ucr.ac.cr/index.php/clinica/article/view/37405
מילת מפתח:Anti -NMDA receptor encephalitis; ovarian teratoma; autoimmune encephalitis; paraneoplastic neurological syndromes
Encefalitis anti receptor NMDA; teratoma ovárico; encefalitis autoinmune; síndromes neurológicos paraneoplásicos