Progreso médico: encefalitis autoinmune contra el receptor de N-metil-D-aspartato asociada a teratomas
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| Autoren: | , , , |
|---|---|
| Format: | artículo original |
| Status: | Versión publicada |
| Publikationsdatum: | 2019 |
| Beschreibung: | Autoimmune encephalitis against the N-methyl-D-aspartate receptor (NMDA-R) is a newly discovered disease that occurs mainly in young women. It is characterized by the presence of autoantibodies against NMDA receptor, specifically against the GluN1 subunit; which generates psychotic symptoms, movement disorders, autonomic dysfunction and even coma. About 50% of patients present ovarian teratoma when completing the studies. This disease is reversible and treatable, therefore diagnosis and treatment are essential. The first line of treatment includes steroids, intravenous G immunoglobulin or plasmapheresis. The second line consists of rituximab and cyclophosphamide. In addition, in the cases where a tumor is documented, the extirpation of it is considered fundamental. |
| Land: | Portal de Revistas UCR |
| Institution: | Universidad de Costa Rica |
| Repositorio: | Portal de Revistas UCR |
| Sprache: | Español |
| OAI Identifier: | oai:portal.ucr.ac.cr:article/37405 |
| Online Zugang: | https://revistas.ucr.ac.cr/index.php/clinica/article/view/37405 |
| Stichwort: | Anti -NMDA receptor encephalitis; ovarian teratoma; autoimmune encephalitis; paraneoplastic neurological syndromes Encefalitis anti receptor NMDA; teratoma ovárico; encefalitis autoinmune; síndromes neurológicos paraneoplásicos |