Magnesium homeostasis: physiological and pathological implications.
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| Autores: | , , , |
|---|---|
| Formato: | artículo original |
| Estado: | Versión publicada |
| Fecha de Publicación: | 2018 |
| Descripción: | Moderate or severe Mg2+ deficiency produces biochemical abnormalities and clinical manifestations associated with skeletal and cardiac muscles, and renal pathologies. Mg2+ is involved in many homeostatic processes such as energetic metabolism, genetic material duplication and transcription, transport of substances across the cell membrane and enzymatic reactions. Regulation of intracellular and extracellular Mg2+ concentration depends on hormonal factors (insulin and parathormone), intestinal factors (paracellular absorption), renal factors (Henle loop reabsorption); as well as reservation deposits in bones and muscles. Even though a wide variety of food contains Mg diet has a low intake of Mg2+. The hypomagnesaemia prod pathological processes such as cramps, arrhythmias and arterial hypertension. This review pretends to describe the basis of the human physiology of Mg2+ functions, absorption regulation excretion and homeostatic pathways, as well as the clinical importance of low intake of Mg2+ effects, which become more prevalent. |
| País: | Portal de Revistas UCR |
| Institución: | Universidad de Costa Rica |
| Repositorio: | Portal de Revistas UCR |
| Lenguaje: | Español |
| OAI Identifier: | oai:portal.ucr.ac.cr:article/34579 |
| Acceso en línea: | https://revistas.ucr.ac.cr/index.php/medica/article/view/34579 |
| Palabra clave: | magnesium homeostasis hypomagnesaemia striated muscle Magnesio hipomagnesemia músculo estriado |