Magnesium homeostasis: physiological and pathological implications.

 

Guardado en:
Sonraí Bibleagrafaíochta
Autores: Murillo Rojas, Fernando, Arrieta Leandro, María Cristina, Ellis Wegley, Catherine, Dobles Bermúdez, Eliott
Formáid: artículo original
Stádas:Versión publicada
Fecha de Publicación:2018
Cur Síos:Moderate or severe Mg2+ deficiency produces biochemical abnormalities and clinical manifestations associated with skeletal and cardiac muscles, and renal pathologies. Mg2+ is involved in many homeostatic processes such as energetic metabolism, genetic material duplication and transcription, transport of substances across the cell membrane and enzymatic reactions. Regulation of intracellular and extracellular Mg2+ concentration depends on hormonal factors (insulin and parathormone), intestinal factors (paracellular absorption), renal factors (Henle loop reabsorption); as well as reservation deposits in bones and muscles. Even though a wide variety of food contains Mg diet has a low intake of Mg2+. The hypomagnesaemia prod pathological processes such as cramps, arrhythmias and arterial hypertension. This review pretends to describe the basis of the human physiology of Mg2+ functions, absorption regulation excretion and homeostatic pathways, as well as the clinical importance of low intake of Mg2+ effects, which become more prevalent.
País:Portal de Revistas UCR
Institiúid:Universidad de Costa Rica
Repositorio:Portal de Revistas UCR
Teanga:Español
OAI Identifier:oai:portal.ucr.ac.cr:article/34579
Rochtain Ar Líne:https://revistas.ucr.ac.cr/index.php/medica/article/view/34579
Access Level:acceso abierto
Palabra clave:magnesium
homeostasis
hypomagnesaemia
striated muscle
Magnesio
hipomagnesemia
músculo estriado