Neurobiology of Posttraumatic Stress Disorder (PTSD) and its Frontostriatal Implications: a short review

 

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Συγγραφείς: Sánchez Castillo, Hugo, Paz-Trejo, Diana, Vazquéz Ramírez, Josselyn, Zarate González, Pavel, Migliaro, Martin
Μορφή: artículo original
Κατάσταση:Versión publicada
Ημερομηνία έκδοσης:2014
Περιγραφή:Throughout its evolutionary course, stress has remained as an adaptive response to stimuli that may jeopardize the integrity of an organism. Within this perspective, we can classify the stressors as psychological,physical or harmful to cardiovascular stability. However, when intense stressful events occur, there is a possibility of developing PTSD. This disorder makes use of the hypothalamic-pituitary-adrenal axis, which is commonly activated during stress and is kept activated even when the stressful stimulus has ended months ago. The consequences of this condition are observed at the neuroendocrine, neurochemical and anatomical level. This review aims to give a brief report of the neurobiology of stress, PTSD, and its implications in various structures,such as the amygdala, hippocampus and prefrontal cortex.
Χώρα:Portal de Revistas UCR
Ίδρυμα:Universidad de Costa Rica
Repositorio:Portal de Revistas UCR
Γλώσσα:Inglés
OAI Identifier:oai:portal.ucr.ac.cr:article/14131
Διαθέσιμο Online:https://revistas.ucr.ac.cr/index.php/actualidades/article/view/14131
Λέξη-Κλειδί :Stress
Cortisol
Trauma
hippocampu
prefrontal cortex