Neurobiology of Posttraumatic Stress Disorder (PTSD) and its Frontostriatal Implications: a short review

 

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書誌詳細
著者: Sánchez Castillo, Hugo, Paz-Trejo, Diana, Vazquéz Ramírez, Josselyn, Zarate González, Pavel, Migliaro, Martin
フォーマット: artículo original
状態:Versión publicada
出版日付:2014
その他の書誌記述:Throughout its evolutionary course, stress has remained as an adaptive response to stimuli that may jeopardize the integrity of an organism. Within this perspective, we can classify the stressors as psychological,physical or harmful to cardiovascular stability. However, when intense stressful events occur, there is a possibility of developing PTSD. This disorder makes use of the hypothalamic-pituitary-adrenal axis, which is commonly activated during stress and is kept activated even when the stressful stimulus has ended months ago. The consequences of this condition are observed at the neuroendocrine, neurochemical and anatomical level. This review aims to give a brief report of the neurobiology of stress, PTSD, and its implications in various structures,such as the amygdala, hippocampus and prefrontal cortex.
国:Portal de Revistas UCR
機関:Universidad de Costa Rica
Repositorio:Portal de Revistas UCR
言語:Inglés
OAI Identifier:oai:portal.ucr.ac.cr:article/14131
オンライン・アクセス:https://revistas.ucr.ac.cr/index.php/actualidades/article/view/14131
キーワード:Stress
Cortisol
Trauma
hippocampu
prefrontal cortex