Evaluación química y biológica del efecto de extractos de plantas contra Plasmodium berghei

 

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Detalles Bibliográficos
Autores: Castro, Oscar, Barrios, Mariano, Chinchilla, Misael, Guerrero, OIga
Formato: artículo original
Estado:Versión publicada
Fecha de Publicación:1996
Descripción:Extracts from thirteen species of plants were evaluated by "in vivo" antimalarial test against Plasmodium berghei effects. Significant activities were observed in the ethyl acetate and aqueous extracts, elaborated of Cedrela tonduzii leaves, Trichilia havanensis and Trichilia americana bades, Neurolaena lobata and Gliricidia sepium leaves and Duranta repens fruits. Compounds identified include flavonoids, coumarins, mellilotic acid and iridoids which sorne kind of biodinamic activity has previously been reported. The flavone quercetin 1 purified from C. tonduzii gave strong antimalarial activity, however, its respective glicosides (quercetin 3-glucoside 2 y robinine 7) showed little significant activity.
País:Portal de Revistas UCR
Institución:Universidad de Costa Rica
Repositorio:Portal de Revistas UCR
Lenguaje:Español
OAI Identifier:oai:portal.ucr.ac.cr:article/21620
Acceso en línea:https://revistas.ucr.ac.cr/index.php/rbt/article/view/21620
Palabra clave:plasmodium berghei
flavones
catechins
coumarin
mellilotic acid
iridoids
resistance