Research in Costa Rica involving human beings and its impact of on the health of costa ricans
保存先:
| 著者: | |
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| フォーマット: | artículo original |
| 状態: | Versión publicada |
| 出版日付: | 2013 |
| その他の書誌記述: | We evaluate the benefits of clinical research carried out in Costa Rica from the published results and a sample of informed consent forms of approved protocols. We found 30 studies on 28 pharmaceuticals and 23 published scientific papers. Results: Of surveyed medical conditions, 19% are directly related to the main causes of mortality and morbidity in our country does not seem to have been necessary for drug registration. A placebo as control was ued in 27% of investigations; of all studies with results, 30% had not published results, 37% published positive results, 17% ambiguous or contradictory results and 13% ended prematurely. Out of the major authors responsible for the publications, 91% were affiliated with research centers abroad. Conclusions: We conclude that there is insufficient evidence to claim that analyzed clinical research has provided a significant benefit to the health of Costa Ricans, represents a significant therapeutic option, or has provided a significant contribution to scientific research in Costa Rica. |
| 国: | Portal de Revistas UCR |
| 機関: | Universidad de Costa Rica |
| Repositorio: | Portal de Revistas UCR |
| 言語: | Español |
| OAI Identifier: | oai:portal.ucr.ac.cr:article/8052 |
| オンライン･アクセス: | https://revistas.ucr.ac.cr/index.php/medica/article/view/8052 |
| キーワード: | Investigación clínica consentimiento informado beneficencia human experimentation informed consent beneficience |