Triple negative breast cancer: generalities, situation in Costa Rica and new trends for its treatment.

 

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Detalles Bibliográficos
Autores: Salinas Meza,, Adriana, Serrano Arias, Bruno, Soto Quesada, Ana Gabriela, Valenciano Fernández, Sofía, Mora Román, Juan José
Formato: artículo original
Estado:Versión publicada
Fecha de Publicación:2018
Descripción:Breast cancer is a clonal proliferation of neoplastic cells that starts in the breast. It is classified according to the histological subtype, the tumor size and the stage. The most aggressive histological subtype is triple negative, being negative for estrogens, progesterone, and human epidermal growth receptors. Throughout the history, treatment for this cancer has changed. Currently, it consists of a combination of radiotherapy, chemotherapy and surgery. However, new changed. Currently, it consists of a combination of being investigated, which have yielded good results in clinical studies. The integration of active and passive immunotherapies such as vaccines and monoclonal antibodies, and the use of poly (ADP or adenosine diphosphate-ribose) polymerase inhibitors, alone or in combination with classical therapies, are alternatives to increase the pharmacotherapeutic possibilities against this type of cancer.
País:Portal de Revistas UCR
Institución:Universidad de Costa Rica
Repositorio:Portal de Revistas UCR
Lenguaje:Español
OAI Identifier:oai:portal.ucr.ac.cr:article/36232
Acceso en línea:https://revistas.ucr.ac.cr/index.php/medica/article/view/36232