Toxoplasma gondii (Eucoccidia: Sarcoystidae) dissemination pattern in rats after oral infection with oocysts of an avirulent strain


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Bibliographic Details
Authors: Guerrero, Olga M, Chinchilla, Misael
Format: artículo original
Status:Versión publicada
Publication Date:1996
Description:Differences in Toxoplasma gondii dissemination in white rats (Sprague Dowley) and mice (Wistar) after oral oocyst inoculation are described. Groups of five anirnals (both hosts) were infected per os with oocysts of the TCR-2 avirulent strain and the dissemination pattero was compared in brain tissue or by serology. Early dissemination was similar in both species. One hr after infection the parasite was present in blood and peritoneal exudate as well as in heart, lupg, liver, spleen, lymph nodes and brain. However, after five days there were important differences between both hosts and after 30 days, the parasite was detected only in rat heart and brain, while in mice it persisted in fluids and all organs
Country:Portal de Revistas UCR
Institution:Universidad de Costa Rica
Repositorio:Portal de Revistas UCR
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Access Level:acceso abierto
Keyword:toxoplasma gondii pathology
natural resistance