Soybean leaf infusion culture media and phytotoxic metabolite production in Macrophomina phaseolina

 

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Egileak: Vaceque-Acosta, Jazmín, Barúa, Javier E., Ruiz-Diaz-Mendoza, Dani Daniel, Romero-Rodríguez, M. Cristina, Macías-Sánchez, Antonio, Flores-Giubi, María Eugenia
Formatua: artículo original
Egoera:Versión publicada
Argitaratze data:2025
Deskribapena:Introduction. The charcoal rot fungus, Macrophomina phaseolina, is a ubiquitous necrotrophic phytopathogen that infecting soybean and other plant species. Despite its significant impact on crops, limited progress has been made in understanding the factors that influence phytotoxic molecule secretion by this phytopathogen. Objective. To evaluate the effect of soybean leaf infusion in the culture medium on the differential secretion of phytotoxic molecules of M. phaseolina. Materials and methods. The study was conducted between 2016 and 2023 at the Departamento de Química Biológica, Universidad Nacional de Asunción, Paraguay. Two fungal isolates were cultured in vitro using potato dextrose broth (PDB) and Czapek-Dox broth media, with or without soybean leaf infusion. Phytotoxic activity of secreted molecules was a using soybean leaf discs. The crude organic extract from the cultures was separated using chromatographic techniques, and purified metabolites were characterized by UHPLC-PDA/MS, HRMS (APGC), HRMSESI, 1HNMR and 13CNMR. Results. Molecules secreted by M. phaseolina FCQ11 cultured in infusion-enriched PDB induced the highest percentage of necrosis. Under these conditions, three differentially secreted metabolites were isolated and identified: (R)-mellein, (3R,4R)-hydroxymellein, and (-)-botryodiplodin. Conclusions. Soybean leaf infusion presence in M. phaseolina growth media stimulates phytotoxic metabolite production and alters the profile of secreted metabolites.
Herria:Portal de Revistas UCR
Erakundea:Universidad de Costa Rica
Repositorio:Portal de Revistas UCR
Hizkuntza:Inglés
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OAI Identifier:oai:portal.revistas.ucr.ac.cr:article/2347
Sarrera elektronikoa:https://revistas.ucr.ac.cr/index.php/ragromeso/article/view/2347
Gako-hitza:fungal phytopathogen
secondary metabolites
bioactive molecules
charcoal rot
hongo fitopatógeno
metabolitos secundarios
moléculas bioactivas
podredumbre carbonosa