Overview and Update on Pharmacotherapy in Epilepsy
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| Autores: | , , , , , |
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| Formato: | artículo original |
| Estado: | Versión publicada |
| Fecha de Publicación: | 2023 |
| Descripción: | Between 5% and 10% of the population will experience a crisis in life, with a higher incidence in childhood and in older adults. A seizure is a paroxysmal episode caused by abnormal, excessive firing or synchronous neuronal activity in the brain. With different forms of manifestation, according to the distribution of the depolarizations. Meanwhile, epilepsy is a disorder accompanied by several recurrent crises, due to an underlying chronic process. The definition of epilepsy will vary according to the clinical context and the encephalograms of each patient. Among the multiple causes, there will be different epileptic syndromes, each with peculiar manifestations and pathologies, suggestive of a specific underlying etiology. Taking this into account, it is estimated that the incidence is approximately 0.3% to 0.5%, with a prevalence of 5 to 30 per 1000 inhabitants. The purpose of this review is to educate and update health professionals, researchers, and even patients. This through a review of the pathophysiological mechanisms of epilepsy and the therapeutic targets of the current anti-seizures, and the new anti-seizures approved by the FDA. In addition, of the adverse effects and the important pharmacological interactions of these. All this, to highlight current advances in pharmacological treatment, the importance of developing new anti-crisis, and to facilitate the choice or combination of the most appropriate anti-seizure for patients. |
| País: | Portal de Revistas UCR |
| Institución: | Universidad de Costa Rica |
| Repositorio: | Portal de Revistas UCR |
| Lenguaje: | Español |
| OAI Identifier: | oai:portal.ucr.ac.cr:article/52807 |
| Acceso en línea: | https://revistas.ucr.ac.cr/index.php/clinica/article/view/52807 |
| Access Level: | acceso abierto |
| Palabra clave: | Anticonvulsants Epilepsy Drug therapy Adverse effects Anticrisis Epilepsia Tratamiento farmacológico Efectos adversos |