Differences by Resistotyping Between C. albicans Strains Isolated from the Oral Cavity of HIV+ and Seronegative Patients

 

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Autores: Rueda-Gordillo PhD, Florencio, Hernández-Solís PhD, Sandra Elena, Gaitán-Cepeda PhD, Luis Alberto, Sánchez-Vargas PhD, Luis Octavio, Lama-González MDent, Esperanza Mercedes, Rodríguez-Fernández MDent, María del Sagrado Corazón
Formato: artículo original
Estado:Versión publicada
Fecha de Publicación:2018
Descripción:Candida albicans is the etiological agent most frequently associated with oral candidiasis in human immunodeficiency virus (HIV) carriers. Strain typification is important to disease epidemiology, particularly with simple, low-cost methodologies such as resistotyping. The present study was designed to use resistotyping to identify possible phenotypic differences between C. albicans strains isolated from the oral cavity of HIV+ and HIV-seronegative patients. Analyses were run using resistotyping (boric acid, cetrimide, sodium periodate, sodium selenite and silver nitrate) to identify phenotypical differences between C. albicans. Descriptive statistics was performed. Of the 149 clones isolated from HIV+ patients the most frequent (47.0%) resistotype was ABCDE. The most frequent resistotype (64.8%) in the 74 clones from HIV-seronegative patients was --CDE. Phenotypic differences were identified between the strains isolated from each group. HIV+ patients exhibited greater strain diversity. Although it has limitations, resistotyping effectively identified differences between C. albicans strains.
País:Portal de Revistas UCR
Institución:Universidad de Costa Rica
Repositorio:Portal de Revistas UCR
Lenguaje:Inglés
OAI Identifier:oai:portal.ucr.ac.cr:article/32882
Acceso en línea:https://revistas.ucr.ac.cr/index.php/Odontos/article/view/32882
Palabra clave:Candida
Candida albicans
HIV
Carriers
Resistotyping
Epidemiology