Volumetric cerebral changes in patients with HIV/AIDS using voxel-based morphometry in magnetic resonance images

 

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Autors: Solís Barquero, Sergio Manuel, Vega Garbanzo, Gustavo Alonso
Format: artículo original
Estat:Versión publicada
Data de publicació:2019
Descripció:The patients with HIV/aids have been object of multiple researches because of the neurological complications they develop during the disease. With images of the brain acquired from magnetic resonance is possible to obtain the volumetric values of the brain area in these patients, doing a voxel-based morphometry. Fourteen magnetic resonance images were acquired from HIV/aids patients (n = 14), and the results were compared with fourteen healthy controls (n = 14). Measures of the volume of the brain using voxel-based morphometry were assessed, comparatively, from the gray matter, white matter, caudate nucleus, hippocampus and corpus callosum. Other variables, as age, were taken into consideration. In conclusion, there is a statistical significant difference in the total cerebral volume (p=0.028) of patients with HIV/aids in comparison with healthy controls. Even though, further studies, and analysis with other variables are needed to establish the behavior of the brain volume of individuals with HIV/aids.
Pais:Portal de Revistas UCR
Institution:Universidad de Costa Rica
Repositorio:Portal de Revistas UCR
Idioma:Español
OAI Identifier:oai:portal.ucr.ac.cr:article/39671
Accés en línia:https://revistas.ucr.ac.cr/index.php/medica/article/view/39671