UPDATE ON TREATMENTS FOR RETINOPATHY OF PREMATURITY
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| Autores: | , , |
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| Formato: | artículo original |
| Estado: | Versión publicada |
| Fecha de Publicación: | 2022 |
| Descripción: | Retinopathy of prematurity is a vasoproliferative pathology that results in an incomplete vascularization of the retina and is one of the main causes of early childhood blindness. This descriptive bibliographic review aims to establish an update on this pathology, as well as to present the current and innovative treatments that are being used around the world. Information consulted in the databases available on the platform of the Library, Documentation and Information System (SIBDI) of the University of Costa Rica was used. The main search for articles was limited to information published from 2016 to 2021. Inclusion criteria: All articles in English that included any of the keywords and were bibliographic reviews, original articles, systematic or meta-analyses. In contrast, articles on other ophthalmological pathologies, other populations that were not premature, case reports and new therapies without robust evidence were excluded. We found that the preferred standard treatment is the use of laser for ablation of pathological neovessels in the peripheral avascular retina. Anti-VEGF therapy has recently been found to have advantages over photocoagulation, being less invasive and stressful to the neonate, with faster response, fewer adverse outcomes, and an acceptable safety profile. There are new promising therapies to counteract the oxidative pathophysiology, including essential fatty acids, propranolol, antioxidants and other agents that, associated with the classically used therapies such as laser photocoagulation and anti-VEGF, are show promising results in the management of retinopathy of prematurity. Finally, when presenting the current situation on the subject, it is concluded that it is important to generate a consensus based on evidence and clinical practice to address ROP in a standardized manner worldwide. Key words: Retinopathy of Prematurity, Vascular Endothelial Growth Factors, Laser Coagulation. Source: MeSH. |
| País: | Portal de Revistas UCR |
| Institución: | Universidad de Costa Rica |
| Repositorio: | Portal de Revistas UCR |
| Lenguaje: | Español |
| OAI Identifier: | oai:portal.ucr.ac.cr:article/50856 |
| Acceso en línea: | https://revistas.ucr.ac.cr/index.php/medica/article/view/50856 |