Evaluación farmacológica y química de Stachytarpheta jamaicensis (Verbenaceae)

 

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Bibliografische gegevens
Auteurs: Rodríguez, Sergia Melita, Castro, Oscar
Formaat: artículo original
Status:Versión publicada
Publicatiedatum:1996
Omschrijving:After intraperitoneal administration of gradual aqueous doses obtained from Stachytarpheta jamaicensis leaves, the following effects were observed in rats: a reduction of motor activity and the alarm reaction, ataxia, sedation, analgesia, anesthesia, ptosis, piloerection, head tremors and a significan! reduction of body temperature of about 8.4°C. Robichaud's sign was present, probably due to sorne muscular relaxation. There were appreciable changes on respiration, with increment on amplitudes and reduction on the frequency, followed by apnea and the death of the animals, probably due to asphysia. Iridoid ipolamiide and the phenylpropanoid glycoside, verbascoside, were identified from the same extracts. Both metabolites have been indicated with potential pharmaceuticals properties in accord with ethnobotanical value attributed to this plant.
Land:Portal de Revistas UCR
Instelling:Universidad de Costa Rica
Repositorio:Portal de Revistas UCR
Taal:Español
OAI Identifier:oai:archivo.portal.ucr.ac.cr:article/21593
Online toegang:https://archivo.revistas.ucr.ac.cr/index.php/rbt/article/view/21593