Evaluación farmacológica y química de Stachytarpheta jamaicensis (Verbenaceae)

 

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Autores: Melita Rodríguez, Sergia, Castro, Oscar
Formato: artículo
Data de Publicação:1996
Descrição:Afier intraperitoneal administration of gradual aqueous doses obtained from Stachytarpheta jamaicensis leaves, the following effects were observed in rats: a reduction of motor activity and the alarm reaction, ataxia, seda tion, analgesia, anesthesia, ptosis, piloerection, head tremors and a significan! reduction of body temperature of about 8.4°C. Robichaud's sign was present, probably due to sorne muscular relaxation. There were appreciable changes on respiration, with increment on amplitudes and reduction on the frequency, followed by apnea and the death of the ani mals, probably due to asphysia. Iridoid ipolamiide and the phenylpropanoid glycoside, verbascoside, were identified from the same extracts. Both metabolites have been indicated with potential pharmaceuticals properties in accord with ethnobotanical value attributed to this plant.
País:Repositorio UNA
Recursos:Universidad Nacional de Costa Rica
Repositorio:Repositorio UNA
Idioma:Español
OAI Identifier:oai:null:11056/23400
Acesso em linha:http://hdl.handle.net/11056/23400
Palavra-chave:FARMACOLOGÍA
VERBENACEAE
PLANTAS MEDICINALES
HIERBAS
VERBASCOSIDE
HERBS
PHARMACOLOGY