Intracellular adaptation of Brucella abortus

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Detalles Bibliográficos
Autores:	Lamontagne, Julie, Forest, Anik, Marazzo, Elena, François, Denis, Butler, Heather, Michaud, Jean-François, Boucher, Lyne, Pedro, Ida, Villeneuve, Annie, Sitnikov, Dmitri, Trudel, Sylvie, Nassif, Najib, Boudjelt, Djamila, Tomaki, Fadi, Chaves-Olarte, Esteban, Guzman-Verri, Caterina, Brunet, Sylvain, Côté-Martin, Alexandra, Hunter, Joanna, Moreno, Edgardo, Paramithiotis, Eustache
Formato:	artículo
Fecha de Publicación:	2009
Descripción:	Macrophages were infected with virulent B. abortus strain 2308 or attenuated strain 19. Intracellular bacteria were recovered at different times after infection and their proteomes compared. The virulent strain initially reduced most biosynthesis and altered its respiration, adaptations reversed later in infection. The attenuated strain was unable to match the magnitude of the virulent strain’s adjustments. The results provide insight into mechanisms utilized by Brucella to establish intracellular infections
País:	Repositorio UNA
Institución:	Universidad Nacional de Costa Rica
Repositorio:	Repositorio UNA
Lenguaje:	Inglés
OAI Identifier:	oai:null:11056/18373
Acceso en línea:	http://hdl.handle.net/11056/18373
Palabra clave:	BRUCELOSIS BRUCELLA BRUCELLA ABORTUS VIRULENCE ENFERMEDADES INFECCIOSAS INTRACELLULAR INFECTION BACTERIAS