Synthesis of Dihydroindolo[2,3-c]carbazole as Potential Telomerase Inhibitor

 

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Autoři: Carvajal Miranda, Yendry, Pérez Salazar, Roy, Varela, Jesús A.
Médium: artículo
Datum vydání:2015
Popis:The dictyodendrins A-E were the first marine natural products that show inhibition of telomerase. A versatile and convergent route was described for the synthesis of derivatives of these pyrrolo[2,3-c]carbazole alkaloids as potential inhibitors of telomerase, by cyclotrimerization [2 + 2 + 2] of ruthenium-catalyzed diynamides diarylacetylenes. © 2015 HeteroCorporation.
Země:Repositorio UNA
Instituce:Universidad Nacional de Costa Rica
Repositorio:Repositorio UNA
Jazyk:Inglés
OAI Identifier:oai:null:11056/17619
On-line přístup:http://hdl.handle.net/11056/17619
Klíčové slovo:TELOMERASA
DICTYODENDRINS A-E
MARINE NATURAL PRODUCTS
DNA SEGMENTS
RNA COMPONENT TERC
SYNTHETIC METABOLITES PROSSESING