Characterization and applications of silver nanoparticles-decorated electrospun nanofibers loaded with polyphenolic extract from rambutan (Nepelium lappaceum)

 

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Detalles Bibliográficos
Autores: Urena-Saborio, Hilary, Rodríguez, Gerardo, Madrigal-Carballo, Sergio, Gunasekaran, Sundaram
Formato: artículo
Fecha de Publicación:2020
Descripción:Rambutan (Nephelium lappaceum) is a traditional fruit originally from Asia and now widely available in Central America. The rind of rambutan is rich in antioxidants, especially polyphenols, which have natural anti-inflammatory and antimicrobial properties. Rambutan polyphenolic extract (RPE) was encapsulated in multi-component electrospun nanofiber (ESNF) templates. These nanofibers were decorated with silver nanoparticles (AgNPs) via in situ electrochemical reduction. The RPE-loaded and AgNPs-decorated ESNF (AgNPs/RPE-ESNF) were evaluated for their hydrophilic, antioxidant, and antimicrobial properties. Results indicate that the addition of RPE to synthetic polycaprolactone (PCL) ESNF improves hydrophilicity and cell attachment and proliferation in vitro. In addition, a synergistic antibacterial and cell proliferation effect between AgNPs and RPE was observed when they were combined in the multi-functionalized ESNF system. The effectiveness of AgNPs/RPE-PCL ESNF as an antioxidant and antibacterial matrix could potentially promote wound healing and also serve as a hybrid scaffold for tissue engineering.
País:Repositorio UNA
Institución:Universidad Nacional de Costa Rica
Repositorio:Repositorio UNA
Lenguaje:Inglés
OAI Identifier:oai:null:11056/22254
Acceso en línea:http://hdl.handle.net/11056/22254
Palabra clave:ANTIBACTERIAL
ANTIOXIDANT
BIOACTIVE
ELECTROSPUN MEMBRANE
NANOPARTICLES
SCAFFOLDS
NANOPARTÍCULAS
ANTIOXIDANTE