Sekikaic Acid and Lobaric Acid Target a Dynamic Interface of the Coactivator CBP/p300

 

Tallennettuna:
Bibliografiset tiedot
Tekijät: Majmudar, Chinmay Y., Højfeldt, Jonas W., Arevang, Carl J., Pomerantz, William C., Gagnon, Jessica K., Schultz, Pamela J., Cesa, Laura C., Doss, Conor H., Rowe, Steven P., Vásquez Chaves, Víctor, Tamayo Castillo, Giselle, Cierpicki, Tomasz, Brooks, Charles L. III, Sherman, David H., Mapp, Anna K.
Aineistotyyppi: artículo original
Julkaisupäivä:2012
Kuvaus:Although there have been recent notable successes in thediscovery of ligands that target stable, high-affinity protein-protein interactions (PPIs), the transient and moderateaffinity PPIs that underpin many fundamental cellularprocesses have proven to be far less tractable for liganddiscovery.[1]Prime examples of this are the dynamic com-plexes formed between DNA-bound transcriptional activa-tors and coactivators that are part of eukaryotic transcriptioninitiation.
Maa:Kérwá
Organisaatio:Universidad de Costa Rica
Repositorio:Kérwá
Kieli:Inglés
OAI Identifier:oai:kerwa.ucr.ac.cr:10669/87973
Linkit:https://onlinelibrary.wiley.com/doi/10.1002/anie.201206815
https://hdl.handle.net/10669/87973
Access Level:acceso abierto
Sanahaku:Coaktivatoren
Depside
Inhibitoren
Protein-Protein-Wechselwirkungen
Sekikasäure

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