Sekikaic Acid and Lobaric Acid Target a Dynamic Interface of the Coactivator CBP/p300

 

में बचाया:
ग्रंथसूची विवरण
लेखकों: Majmudar, Chinmay Y., Højfeldt, Jonas W., Arevang, Carl J., Pomerantz, William C., Gagnon, Jessica K., Schultz, Pamela J., Cesa, Laura C., Doss, Conor H., Rowe, Steven P., Vásquez Chaves, Víctor, Tamayo Castillo, Giselle, Cierpicki, Tomasz, Brooks, Charles L. III, Sherman, David H., Mapp, Anna K.
स्वरूप: artículo original
प्रकाशन तिथि:2012
विवरण:Although there have been recent notable successes in thediscovery of ligands that target stable, high-affinity protein-protein interactions (PPIs), the transient and moderateaffinity PPIs that underpin many fundamental cellularprocesses have proven to be far less tractable for liganddiscovery.[1]Prime examples of this are the dynamic com-plexes formed between DNA-bound transcriptional activa-tors and coactivators that are part of eukaryotic transcriptioninitiation.
देश:Kérwá
संस्थान:Universidad de Costa Rica
Repositorio:Kérwá
भाषा:Inglés
OAI Identifier:oai:kerwa.ucr.ac.cr:10669/87973
ऑनलाइन पहुंच:https://onlinelibrary.wiley.com/doi/10.1002/anie.201206815
https://hdl.handle.net/10669/87973
Access Level:acceso abierto
संकेत शब्द:Coaktivatoren
Depside
Inhibitoren
Protein-Protein-Wechselwirkungen
Sekikasäure