Sekikaic Acid and Lobaric Acid Target a Dynamic Interface of the Coactivator CBP/p300

 

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Detaylı Bibliyografya
Yazarlar: Majmudar, Chinmay Y., Højfeldt, Jonas W., Arevang, Carl J., Pomerantz, William C., Gagnon, Jessica K., Schultz, Pamela J., Cesa, Laura C., Doss, Conor H., Rowe, Steven P., Vásquez Chaves, Víctor, Tamayo Castillo, Giselle, Cierpicki, Tomasz, Brooks, Charles L. III, Sherman, David H., Mapp, Anna K.
Materyal Türü: artículo original
Yayın Tarihi:2012
Diğer Bilgiler:Although there have been recent notable successes in thediscovery of ligands that target stable, high-affinity protein-protein interactions (PPIs), the transient and moderateaffinity PPIs that underpin many fundamental cellularprocesses have proven to be far less tractable for liganddiscovery.[1]Prime examples of this are the dynamic com-plexes formed between DNA-bound transcriptional activa-tors and coactivators that are part of eukaryotic transcriptioninitiation.
Ülke:Kérwá
Kurum:Universidad de Costa Rica
Repositorio:Kérwá
Dil:Inglés
OAI Identifier:oai:kerwa.ucr.ac.cr:10669/87973
Online Erişim:https://onlinelibrary.wiley.com/doi/10.1002/anie.201206815
https://hdl.handle.net/10669/87973
Anahtar Kelime:Coaktivatoren
Depside
Inhibitoren
Protein-Protein-Wechselwirkungen
Sekikasäure

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