Palladium-Catalyzed One-Pot Conversion of Aldehydes and Ketones into 4-Substituted Homopropargyl Alcohols and 5-En-3-yn-1-ols†
में बचाया:
| लेखकों: | , |
|---|---|
| स्वरूप: | artículo original |
| प्रकाशन तिथि: | 2017 |
| विवरण: | Sequential treatment of 2,3-dichloropropene with magnesium and n-BuLi generated the equivalent of 1,3- dilithiopropyne, which adds regiospecifically to aldehydes and ketones to produce homopropargyl alcohols. The lithium acetylide intermediate formed in this protocol can be further reacted with aromatic and vinyl halides, under palladium catalysis, to produce 4-substituted homopropargyl alcohols and 5-en-3-yn-1-ols, respectively, in one-pot with good overall yields. |
| देश: | Kérwá |
| संस्थान: | Universidad de Costa Rica |
| Repositorio: | Kérwá |
| भाषा: | Inglés |
| OAI Identifier: | oai:kerwa.ucr.ac.cr:10669/87985 |
| ऑनलाइन पहुंच: | https://pubs.acs.org/doi/10.1021/acs.joc.7b01529 https://hdl.handle.net/10669/87985 https://doi.org/10.1021/acs.joc.7b01529 |
| संकेत शब्द: | Alcohols Allenes Aromatic compounds Hydrocarbons Palladium |