South American snake venom proteins antigenically-related to Bothrops asper myotoxins.

 

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Detalles Bibliográficos
Autores: Lomonte, Bruno, Furtado, María de Fátima, Rovira Rodríguez, María Elena, Carmona Morera, Elena, Rojas Céspedes, Gustavo, Aymerich Blen, Rodrigo, Gutiérrez, José María
Formato: artículo original
Fecha de Publicación:1990
Descripción:the presence of proteins antigenically related to Bothrops asper myotoxins in various snake venoms, mainly from South America, was investigated by using poluclonal and monoclonal antibodies. 2. Myotoxin-like components were detected in the bothrops venoms from South america, and in the venoms of Crotalus atrox (North america), Trimerusurus flavoviridis (Japan), and Micrurus alleni (Costa Rica). 3. Cross-reactive components detected in several Bothrops venoms show a common subunit of 15-16 LDa by sodium dodcyl sulphate-polyacrylamide gel electrophoresis, although significant charge variations are evident by immunoelectrophoresis. 4. It is concluded that proteins antigenically related to B. asper nyotoxins are relatively common in the genus Bothrops and, in the light of findings discussed, are likely to posses myotoxic activity.
País:Kérwá
Institución:Universidad de Costa Rica
Repositorio:Kérwá
OAI Identifier:oai:kerwa.ucr.ac.cr:10669/73014
Acceso en línea:http://www.scielo.br/scielo.php?script=sci_serial&pid=0100-879X&lng=en&nrm=iso
https://hdl.handle.net/10669/73014
Palabra clave:Myotoxin
Snake venom
Bothrops
Cross-reactions