Isomerization of fatty acids: A cellular barrier mechanism in nanotechnology?

 

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Detalles Bibliográficos
Autores: González Paz, Rodolfo, Jose-Roberto, Vega-Baudrit, Cadiz, Virginia
Formato: artículo
Fecha de Publicación:2017
Descripción:This work is a kinetic study of the coupling reaction of 2-mercaptoethanol with methyl undecenoate and with methyl oleate through " click " chemistry. Reversibility and reactivity of each system were followed through Fourier Transform Infrared Spectroscopy and ATR conversion (FTIR-ATR) and Nuclear Magnetic Resonance Spectroscopy (1 H NMR). It was proved that the addition of thiol to the alkene may be reversible, that it depends on factors such as the structure of the alkene and the concentration of thiol or photoinitiator, but that it is mainly affected by the isomerization process in fatty acids and the reactivity of each configuration (cis or trans). It was concluded that under our " click " chemical experimental conditions, the cis form of methyl oleate is more reactive than the trans form. Finally, the plausibility of applying this process in nanotechnology is discussed as a cellular barrier mechanism to avoid internalization of toxic nanoparticles
País:Repositorio UNA
Institución:Universidad Nacional de Costa Rica
Repositorio:Repositorio UNA
Lenguaje:Inglés
OAI Identifier:oai:https://repositorio.una.ac.cr:11056/17411
Acceso en línea:http://hdl.handle.net/11056/17411
Access Level:acceso abierto
Palabra clave:ISOMERIZATION
ÁCIDOS GRASOS
THIYL RADICALS
CELULAR MEMBRANE
NANOTECNOLOGÍA