(1S,3R)-N-{(3S,10S,12S,13R,17R)-12-Hydroxy-17- [(R)-5-hydroxypentan-2-yl]-10,13-dimethylhexa- decahydro-1H-cyclopenta[a]phenanthren-3-yl}- adamantane-1-carboxamide 0.25-hydrate

 

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Autors: Campos Fernández, Cristian Saúl, Procúpez Schtirbu, Rolando, Soto Tellini, Victor Hugo, Salazar Camacho, Juan Carlos, Jancik, Vojtech
Format: artículo original
Data de publicació:2022
Descripció:The title compound, C 35H 57 NO 3 0.25H 2O, was synthesized from deoxycholic acid followed by a protection, a Mitsonobu substitution, a Staudinger reduction, formation of an amide and final reduction in the lateral chain. The compound crystallizes in the P1 space group with four steroid molecules and one water molecule in the triclinic cell unit. The crystal structure features O—H O hydrogen bonding. The crystal studied was refined as a non-merohedral twin
Pais:Kérwá
Institution:Universidad de Costa Rica
Repositorio:Kérwá
Idioma:Inglés
OAI Identifier:oai:kerwa.ucr.ac.cr:10669/87554
Accés en línia:https://iucrdata.iucr.org/x/issues/2022/10/00/bt4124/index.html
https://hdl.handle.net/10669/87554
Paraula clau:Química Cristalografía
biological activity
crystal structure
bile salts