Somatic instability of the expanded CTG triplet repeat in myotonic dystrophy type 1 is a heritable quantitative trait and modifier of disease severity

Παρόμοια τεκμήρια

• Longitudinal increases in somatic mosaicism of the expanded CTG repeat in myotonic dystrophy type 1 are associated with variation in age-at-onset
  ανά: Morales Montero, Fernando
  Έκδοση: (2020)
• A polymorphism in the MSH3 mismatch repair gene is associated with the levels of somatic instability of the expanded CTG repeat in the blood DNA of myotonic dystrophy type 1 patients
  ανά: Morales Montero, Fernando
  Έκδοση: (2016)
• High levels of somatic DNA diversity at the myotonic dystrophy type 1 locus are driven by ultra-frequent expansion and contraction mutations
  ανά: Higham, Catherine
  Έκδοση: (2012)
• MSH3 modifies somatic instability and disease severity in Huntington’s and myotonic dystrophy type 1
  ανά: Flower, Michael
  Έκδοση: (2019)
• Disease-associated CAG·CTG triplet repeats expand rapidly in non-dividing mouse cells, but cell cycle arrest is insufficient to drive expansion
  ανά: Gomes Prereira, Mario
  Έκδοση: (2014)